Labels a dimeric protein produced by and used within the thyroid gland. This antibody is useful in positive identification of metastatic thyroid carcinomas of the papillary and follicular types, but technical issues with these antibodies often producing nonspecific signal make the combination of TTF-1 and PAX-8 expression a better marker for these tumors.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.