Identifies a glycoprotein restricted to the cytoplasm of acinar and ductal epithelia of normal, benign, or malignant prostate tissue. It is a highly sensitive and specific marker of metastatic prostate adenocarcinoma. PSA from prostatic cancer has been shown to be immunologically and biochemically similar to that of normal prostate tissue. Because the antibody does not react with tumors of non-prostatic origin, the antibody is useful for determining if an isolated metastasis is of prostatic origin.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.