Identifies Keratin 5/14, p63 protein, and P504S and is useful for diagnosing prostatic intraepithelial neoplasia (PIN) and/or prostate carcinoma, especially in difficult cases with limited tissue. P504 stains prostate adenocarcinoma and atypical adenomatous hyperplasia, while p63 and cytokeratin high molecular weight stain basal cells of all normal (negative markers) and benign prostate glands.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.