Plasma cell (cytoplasmic) Add-On Flow Panel

Available as global and tech-only. Markers are CD19, CD20, CD38, CD45, CD56, CD117, CD138, ckappa, clambda.

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CLINICAL SIGNIFICANCE: Useful to aid in diagnosis of plasma cell and B cell neoplasms.

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Synonyms

Turnaround Time

Global: 24-48 hrs, Tech-Only: 24 hrs

Methodology

Flow Cytometry

Specimen Requirements

Bone Marrow Aspirate: 1-2 mL EDTA. Sodium heparin is acceptable. Lithium heparin or ACD (pale yellow/no gel separator) is not acceptable. Please provide recent CBC report.

Peripheral Blood: 1-2 mL EDTA. Sodium heparin is acceptable. Lithium heparin or ACD (pale yellow/no gel separator) is not acceptable. Please provide recent CBC report.

Fresh Bone Marrow Core Biopsy: 1-2cm core (length) tissue in RPMI

Fresh/Unfixed Tissue: 0.2 cm3 minimum in RPMI

Fluids and FNAs: Equal parts RPMI and specimen volume

CSF: 1-2 mL recommended

Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.

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Storage and Transportation

Specimens should be received at Vitro Molecular within 72 hours from collection to assure sample integrity and acceptable cell viability. Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

CPT Codes

88184(x1), 88185(x8), 88188(x1)