This antibody recognizes two isoforms of p63. The Np63 (p40) isoform is predominant in basal and myoepithelial cells, as well as squamous cell carcinomas of lung and other sites. It is a more specific marker than p63 and eliminates potentially misinterpreting a p63-positive adenocarcinoma as squamous cell carcinoma.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.