Identifies a nuclear transcription factor expressed by early embryonic cells, germ cells, and stem cells. It is a nuclear marker of classical seminoma and embryonal carcinoma. It has excellent sensitivity and specificity for these two tumors and can be used as the screen for these neoplasms when dealing with a metastatic tumor of unknown origin.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.