Identifies the intermediate filament protein comprising neurofilaments, which are expressed exclusively within tumors of neural origin or tumors displaying neuronal differentiation, such as neuroblastoma, medulloblastoma, and retinoblastoma. This antibody labels neurons, neuronal processes and peripheral nerves, as well as sympathetic ganglion cells and adrenal medulla. The cell bodies of neurons are weakly stained.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.