Identifies a neuronal nuclear antigen expressed by most neuronal cell types throughout the nervous system, including the cerebellum, cerebral cortex, hippocampus, thalamus, spinal cord, and neurons in the peripheral nervous system, including dorsal root ganglia, sympathetic chain ganglia, and enteric ganglia. It is a sensitive and specific marker of neuronal differentiation in brain tumors.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.