Identifies epithelial glycoprotein 2, a cell surface protein present on epithelial cells but not on mesothelial cells. The expression of this protein has been demonstrated to help in the distinction of adenocarcinoma (positive) from mesothelioma (negative). MOC31 also does not label liver as well as hepatocellular carcinoma, therefore it is useful in the differential diagnosis of liver metastases versus hepatocellular carcinomas.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.