Identifies a cell surface glycoprotein expressed by mesothelial cells and malignant mesothelioma, but also by non-mucionous ovarian carcinomas, breast carcinomas, pancreatic adenocarcinomas, and squamous tumors of the esophagus and cervix. Displays significantly less specificity for mesotheliomas than other markers such as WT-1, calretinin, and podoplanin.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.