Identifies a breast-associated glycoprotein that is a sensitive and specific marker of carcinomas primary to the breast. In normal breast tissue, this antibody labels breast ductal and lobular epithelial cells; in tumor cells, it reacts with all types of breast adenocarcinoma regardless of tumor differentiation and type. This protein can also be expressed in a subset of salivary gland tumors as well as ovarian carcinomas, but adenocarinomas from other organs rarely express mammaglobin. It can help in the identification of primary cites of carcinomas.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.