Identifies Inhibin-alpha, a peptide hormone which forms a pituitary FSH secretion inhibitor. It is expressed by granulosa cells and granulosa cell and other sex cord stromal tumors, as well as adrenal cortical cells and tumors. It stains most adrenal tumors but no cases of renal cell carcinomas and is useful in differentiating between adrenocortical tumors and renal cell carcinoma.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.