Identifies hepatitis B infected cells in the liver and other cites. The core antigens of hepatitis B virus are localized within the nuclei, whereas surface antigens are present in the cytoplasm of the infected cells. Antibodies to the core antigens are detected in blood after several weeks, as opposed to surface antigens which appear in circulation at an early stage of infection.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.