Identifies one of the two transmembrane proteins exposed on the outer surface of normal human erythrocytes and a marker of erythroid differentiation in myeloid processes. This antibody reacts with an epitope located on the extracellular domain of glycophorin A and does not cross-react with glycophorin D. Glycophorin A is expressed during all stages of differentiation in human astrocytes and once it is maximally expressed, the quantity of glycophorin A in each red blood cell remains constant. It has also been located in the blast cells of cases of erythroleukemia, but does not react in cases of acute lymphoblastic and myeloblastic leukemia.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.