A nuclear transcription factor that is reportedly the first nuclear marker of endothelial differentiation. It labels hemangiomas, angiosarcomas, Kaposis sarcoma, and Ewings and Merkel cell carcinoma. It is also expressed in normal endothelial cells, megakaryocytes, and normal breast epithelia.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.