A cell surface-associated protein expressed at relatively high levels by cytotoxic/suppressor T cells, and at lower levels by gamma-delta T cells and NK cells. It is also detected on most thymocytes, a subpopulation of null cells, and bone marrow cells. It is aberrantly decreased in a subset of T-cell and NK cell neoplasms and is useful in evaluating T-cell lymphomas.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.