A cell surface-associated protein that is the receptor for interleukin-2 and strongly expressed on the neoplastic T cells of adult T cell leukemia/lymphoma and anaplastic large cell lymphoma, hairy cell leukemia, classical Hodgkin lymphoma, and a subset of other peripheral T-cell lymphomas. The aberrant expression of CD25 on mast cells is also an important immunophenotypic clue to the diagnosis of systemic mastocytosis.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.