A transmembrane protein that acts as a scavenger receptor and is restricted in expression to the monocytic/macrophage lineage. It is present on all circulating monocytes and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhans cells.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.