Identifies the interleukin-3 receptor and labels plasmacytoid dendritic cells. It is useful in diagnosing neoplasms derived from these cells and is also expressed at variable intensity in all classical hairy cell leukemia, most B-ALLs, and in a subset of AMLs. It is also useful for diagnosing reactive conditions such as histiocytic necrotizing lymphadentis.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.