Identifies C cells of the thyroid and medullary thyroid carcinomas, and is used to demonstrate early or microscopic medullary thyroid cancer (MTC), an MTC in the absence of amyloid deposits, distinguish non-typical forms of MTC from anaplastic carcinoma or malignant lymphoma, to differentiate MTC with microfollicular or papillary patterns from thyroid follicular and papillary mechanisms, and to identify C-cell hyperplasia in association with hypercalcemia of diverse etiologies.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.