This antigen is present in normal tissues of the ductal epithelium of the breast, kidney, salivary gland, sweat glands, respiratory epithelium of the lung, colon epithelium, pancreatic acini and ducts, biliary epithelium in the liver, and prostate epithelium. It is positive for gastrointestinal carcinomas, transitional cell carcinomas of the bladder, endometrial adenocarcinomas, thyroid paillary, gallblader carcinomas, and lung carcinomas, including adenocarcinomas, bronchoalveolar cell carcinomas, and squamous and small cell carcinomas.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.