Stains a nuclear protein expressed by normal germinal center B cells, the follicular cells and interfollicular cells in follicular lymphoma, a large subset of diffuse large B cell lymphomas, all Burkitt lymphomas, and the majority of Reed-Sternberg cells in nodular lymphocyte predominant Hodgkin lymphoma. Rarely stains mantle cell lymphoma and mucosa-associated lymphoid tissue lymphoma and BCL6 expression is absent in peripheral T-cell lymphomas.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.