B-Cell Gene Rearrangement IGH

Detection of clonal IgH gene rearrangements by PCR of IgH framework regions 1, 2, 3 and joining regions.

Synonyms
Turnaround Time
8 days
Methodology
Molecular
Specimen Requirements
  • Peripheral blood: 5 mL in EDTA tube.
  • Bone marrow: 2 mL in EDTA tube.
  • FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
  • Fresh tissue: Two pieces minimum, 0.2 cm3 in RPMI.
  • Storage and Transportation

    Refrigerate fresh tissue until shipping. For all specimens, use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

    CPT Codes
    81261